Peptide P60

SKU: orb2942835

Description

Peptide P60 is a cell-permeable FOXP3 inhibitor that blocks its nuclear translocation and transcriptional suppression, reducing Treg immunosuppression while enhancing effector T cell responses. This action, studied in vitro and in models mimicking scurfy mice, suggests potential applications in cancer and vaccine immunology research.

Research Area

Signal Transduction

Key Properties

• Target: NF-κB
• CAS Number: 1319725-20-6
• MW: 1994.34
• Formula: C₉₅H₁₃₂N₂₄O₂₀S₂
• SMILES: C([C@@H](C(=O)N1[C@H](C(N[C@@H](CC2=CC=CC=C2)C(N[C@@H](CC3=CC=CC=C3)C(N[C@H](C(N[C@@H](CCSC)C(O)=O)=O)C)=O)=O)=O)CCC1)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC4=CC=CC=C4)NC([C@@H](NC([C@@H](NC([C@H](CC5=CC=CC=C5)NC([C@@H](NC([C@H](CCCNC(=N)N)N)=O)CC(O)=O)=O)=O)CCC(N)=O)=O)CO)=O)=O)CCCNC(=N)N)=O)CCCCN)=O)CCSC)=O)C=6C=7C(NC6)=CC=CC7

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

166450473