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p38α inhibitor 2

SKU: orb1694117

Description

P38α Inhibitor 2 is a potent and selective p38α MAPK inhibitor with a pIC50 of 9.6. It shows promising selectivity, exhibiting minimal off-target activity against a broad panel of kinases and biological targets, though it demonstrates hERG channel inhibition at 27 μM. This compound is a valuable tool for investigating p38α signaling in cellular and inflammatory disease models.

Research Area

Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

Key Properties

CAS Number1095003-80-7
MW475.58
FormulaC27H33N5O3
SMILESCNCCOc1ccccc1C(C)(C)Nc1nccn(-c2cc(ccc2C)C(=O)NC2CC2)c1=O
Targetp38 MAPK,Others

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information