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P-gp inhibitor 5

SKU: orb1686432

Description

P-gp inhibitor 5 is a potent small molecule that reverses multidrug resistance by inhibiting P-glycoprotein, restoring the efficacy of chemotherapeutics like Vincristine and Paclitaxel in resistant cell lines such as ABCB1/Flp-In-293 and KBvin. Its application is valuable for in vitro MDR cancer research, particularly in studying P-gp-mediated drug efflux and combination therapies.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number2451298-06-7
MW517.98
FormulaC28H20ClNO5S
SMILESO(C(C)=O)C1=C2C(=C(NC(=O)C3=C(Cl)C=CC=C3)OC2=CC(=C1)C4=CC=C(OC)C=C4)C5=CC=CS5
TargetP-gp,Others

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

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Protocol Information

P-gp inhibitor 5 (orb1686432)

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25 mg
$ 1,560.00
50 mg
$ 2,020.00
100 mg
$ 2,540.00
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