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P-gp inhibitor 3

SKU: orb1744754

Description

P-gp Inhibitor 3 is a potent small molecule that reverses multidrug resistance by stimulating P-glycoprotein ATPase activity, which paradoxically inhibits its efflux function. This action enhances the intracellular accumulation and efficacy of chemotherapeutics like paclitaxel in both cellular and animal models of cancer.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Images & Validation

Key Properties

MW782.06
FormulaC48H67N3O6
SMILESCCN1CCN(CC1)C(=O)CCC(=O)OC[C@]2(C3CC[C@@]4(C([C@]3(CC5=C2ON=C5)C)CC=C6[C@]4(CC[C@@]7(C6CC(CC7)(C)C)C(=O)OCC8=CC=CC=C8)C)C)C
TargetOthers,P-gp

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Protocol Information