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P-gp inhibitor 15

SKU: orb2278085

Description

P-gp Inhibitor 15 is a potent, nonsubstrate inhibitor that blocks P-glycoprotein function by suppressing its ATPase activity and Rhodamine123 efflux in vitro. It demonstrates in vivo efficacy by synergistically enhancing paclitaxel's antitumor activity in KBV xenograft models, supporting research in multidrug resistance and combination cancer therapy.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Images & Validation

Key Properties

MW572.86
FormulaC35H60N2O4
TargetOthers,P-gp

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information