Ouabain octahydrate

SKU: orb1745280

Description

Ouabain octahydrate (Acocantherine) is a cardiac glycoside that inhibits Na(+)/K(+) ATPase. Ouabain octahydrate regulates transcription of MDR (increase, Pgp) and MRP (increase MRP1 and decrease CFTR, cyctic fibrosis transport receptor or cAMP-activated Cl- channel) genes, also alters localization of MRP1.

Research Area

Cell Biology, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 11018-89-6
• MW: 728.77
• Purity: 99.90%
• Formula: C₂₉H₄₄O₁₂·8H₂O
• SMILES: O.O.O.O.O.O.O.O.CC1OC(OC2CC(O)C3(CO)C4C(O)CC5(C)C(CCC5(O)C4CCC3(O)C2)C2=CC(=O)OC2)C(O)C(O)C1O
• Target: ATPase,Autophagy
• Solubility: H2O:2.08 mg/mL (2.85 mM);DMSO:126 mg/mL (172.89 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (5.49 mM)

Storage & Handling

• Storage: store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Disclaimer: For research use only

Alternative Names

inhibit, Ouabain, Ouabain Octahydrate, Ouabain octahydrate, Na+/K+ ATPase, Na+/K+-ATPase, Inhibitor, G-Strophanthin, Acocantherine, Autophagy, Sodium potassium pump

Compound Identifiers

PubChem CID

22495228