Rostafuroxin

SKU: orb1305256

Description

Rostafuroxin (PST 2238) is a research compound investigated for the treatment of essential hypertension. It functions as a selective antagonist of the endogenous ouabain receptor, with studies demonstrating its antihypertensive effects in both in vitro assays and in vivo animal models.

Research Area

Infectious Disease & Virology, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 156722-18-8
• MW: 374.51
• Purity: 99.08%
• Formula: C₂₃H₃₄O₄
• SMILES: C[C@]12CC[C@H]3[C@@H](CC[C@@H]4CC(O)CC[C@]34C)[C@]1(O)CCC2(O)c1ccoc1
• Target: ATPase,RSV
• Solubility: DMSO:50 mg/mL (133.51 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.34 mM)

Bioactivity

• Target IC50:
  Na+-ATPase:1.5 nM|K+-ATPase:1.5 nM

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

digitoxigenin, antihypertensive, ATP1A1, inhibit, Ouabain, Na+/K+ ATPase, Na+/K+-ATPase, Inhibitor, EGFR, RSV-GFP, RSV, Rostafuroxin, Respiratory syncytial virus, Sodium potassium pump, Tyr845, PST 2238, PST2238, PST-2238, phosphorylation

Compound Identifiers

PubChem CID

91895238