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Catalog Number | orb1300847 |
---|---|
Category | Small Molecules |
Description | NVP-BHG712 |
CAS Number | 940310-85-0 |
Purity | 97.96% |
MW | 503.48 |
SMILES | N(C1=C2C(=NC(=N1)C=3C=CC=NC3)N(C)N=C2)C4=CC(C(NC5=CC(C(F)(F)F)=CC=C5)=O)=CC=C4C |
Formula | C26H20F3N7O |
Biological Activity | NVP-BHG712 is a specific EphB4 inhibitor with ED50 of 25 nM that discriminates between VEGFR and EphB4 inhibition; also shows activity against c-Raf, c-Src and c-Abl with IC50 of 0.395 μM, 1.266 μM and 1.667 μM, respectively. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
> 98%(HPLC) | |
940310-85-0 |
> 98% (HPLC) | |
2245892-85-5 |
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