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NVP-ADW742

SKU: orb1224998

Description

NVP-ADW742 is an IGF-1R inhibitor with IC50 of 0.17 μM, >16-fold more potent against IGF-1R than InsR; little activity to HER2, PDGFR, VEGFR-2, Bcr-Abl and c-Kit.

Images & Validation

Key Properties

CAS Number475489-15-7
MW453.38
Purity>98% (HPLC)
FormulaC28H31N5O
SMILESNC1=NC=NC2=C1C(=CN2C1CC(CN2CCCC2)C1)C1=CC(OCC2=CC=CC=C2)=CC=C1
TargetIGF-1R
SolubilityDMSO: > 10mM

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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NVP-ADW742 (orb1224998)

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