You have no items in your shopping cart.
You have no items in your shopping cart.
Catalog Number | orb1306290 |
---|---|
Category | Small Molecules |
Description | Nutlin-3 |
CAS Number | [548472-68-0] |
Purity | 99.89% |
MW | 581.49 |
SMILES | COc1ccc(C2=NC(C(N2C(=O)N2CCNC(=O)C2)c2ccc(Cl)cc2)c2ccc(Cl)cc2)c(OC(C)C)c1 |
Formula | C30H30Cl2N4O4 |
Biological Activity | Nutlin-3 is an MDM2 antagonist.Nutlin-3 inhibits the MDM2-p53 interaction (IC50: 0.09 μM) and activates p53. Antiproliferative agent; chemotherapeutic agent; induces apoptosis in Y cells. |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
98.00% | |
37.8 kDa (predicted); 37.5 kDa (reducing conditions) |