NIK (N) Antibody, Rabbit Polyclonal

SKU: orb67296

Description

Rabbit polyclonal to NIK.NF-kappa-beta-inducing kinase (NIK) is also known as Mitogen-activated protein kinase kinase kinase14 (MAP3K14), which belongs to the protein kinase superfamily, STE Ser/Thr protein kinase familyand MAP kinase kinase kinase subfamily. NIK contains 1 protein kinase domain. NIK can be activatedby lymphotoxin beta, which seems to be exclusively involved in the activation of NF-kappa-B and itstranscriptional activity. NIK promotes proteolytic processing of NFKB2/P100, which leads to activationof NF-kappa-B via the non-canonical pathway. NIK can function in a receptor-selective manner.

Research Area

Epigenetics, NF-kB, Neuroscience, Signaling Pathways

Images & Validation

• Tested Applications: WB
• Dilution Range: WB:1:500-1:2000
• Reactivity: Human

Key Properties

• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: N-terminal region of human NIK
• Molecular Weight: 104
• Purity: Affinity purification
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: 0.01% NaN3
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

anti-NIK antibody,anti-Mitogenactivated protein kinase kinase kinase 14 antibody,anti-NFkappabetainducing kinase antibody,anti-HsNIK antibody,anti- Serine antibody,anti-threonineprotein kinase NIK antibody,anti-MAP3K14 antibody

Western blot analysis of total cell extracts from human Hela using NIK antibody

Quick Database Links

UniProt

Q99558