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Catalog Number | orb67296 |
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Category | Antibodies |
Description | Rabbit polyclonal to NIK.NF-kappa-beta-inducing kinase (NIK) is also known as Mitogen-activated protein kinase kinase kinase14 (MAP3K14), which belongs to the protein kinase superfamily, STE Ser/Thr protein kinase familyand MAP kinase kinase kinase subfamily. NIK contains 1 protein kinase domain. NIK can be activatedby lymphotoxin beta, which seems to be exclusively involved in the activation of NF-kappa-B and itstranscriptional activity. NIK promotes proteolytic processing of NFKB2/P100, which leads to activationof NF-kappa-B via the non-canonical pathway. NIK can function in a receptor-selective manner. |
Clonality | Polyclonal |
Species/Host | Rabbit |
Conjugation | Unconjugated |
Reactivity | Human |
Buffer/Preservatives | 0.01% NaN3 |
Purity | Affinity purification |
Immunogen | N-terminal region of human NIK |
UniProt ID | Q99558 |
MW | 104 |
Tested applications | WB |
Dilution range | WB:1:500-1:2000 |
Storage | -20°C |
Alternative names | anti-NIK antibody,anti-Mitogenactivated protein ki Read more... |
Note | For research use only |
Western blot analysis of total cell extracts from human Hela using NIK antibody