NF-κB Antibody

SKU: orb3131439

Description

PE0116 is a fully humanized CD137 agonistic monoclonal antibody, generated from immunized Harbor H2L2 transgenic mice. Acting as a ligand blocker, PE0116 activates NF-κB signaling, which significantly enhances T cell proliferation and increases cytokine secretion in vitro. In the MC38 tumor model, PE0116 demonstrates strong antitumor activity.

Research Area

Signal Transduction

Key Properties

• Antibody Type: Inhibitor Antibody
• Clonality: Monoclonal
• Target: NF-κB
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

NF-κB