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Multi-kinase inhibitor 4

SKU: orb2695407

Description

Compound 14 is a potent, orally bioavailable multi-kinase inhibitor targeting VEGFRs (FLT1/KDR/FLT4), FLT3, and PDGFRs with low nanomolar IC50 values. It is a valuable research tool for investigating angiogenesis and oncogenesis in both cellular assays and in vivo cancer models.

Research Area

Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

Key Properties

CAS Number2648279-77-8
MW440.50
FormulaC25H24N6O2
SMILESO=C(NC=1ON=C(C1)C(C)(C)C)CC2=CC=C(C=C2)N3C=NC=4C=C(C=CC43)C=5C=NNC5
TargetPDGFR,FLT

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

Protocol Information