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Catalog Number | orb1305516 |
---|---|
Category | Small Molecules |
Description | PP121 |
CAS Number | 1092788-83-4 |
Purity | 99.67% |
MW | 319.36 |
SMILES | NC1=C2C(=NN(C2=NC=N1)C3CCCC3)C=4C=C5C(=NC4)NC=C5 |
Formula | C17H17N7 |
Biological Activity | PP-121 is a multi-targeted inhibitor of PDGFR (IC50: 2 nM), Hck (IC50: 8 nM), mTOR (IC50: 10 nM), VEGFR2(IC50: 12 nM), Src (IC50: 14 nM) and Abl (IC50: 18 nM) , also inhibits DNA-PK (IC50: 60 nM). |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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