Mouse ICAM-3 Antibody

• Catalog Number: orb137661
• Category: Antibodies
• Description: Mouse monoclonal to ICAM-3. Intercellular adhesion molecule 3 (ICAM3) also known as CD50 (Cluster of Differentiation 50), is a type I transmembrane glycoprotein, which normally contain 2-9 immunoglobulin-like C2-type domains, and binds to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. ICAM-3 has previously been implicated in apoptotic cell clearance, although its precise role in the clearance process is ill defined.
• Clonality: Monoclonal
• Species/Host: Mouse
• Isotype: IgG1/k
• Conjugation: Unconjugated
• Reactivity: Human
• Form/Appearance: Each vial contains 100 µl 1 mg/ml purified monoclonal antibody in PBS containing 0.09% sodium azide.
• UniProt ID: P32942
• Tested applications: ELISA, FC, ICC, IHC-Fr, IP, WB
• Antibody Type: Primary Antibody
• Clone Number: BH10
• Source: BH10 is a mouse monoclonal IgG1/k antibody derived by fusion of mouse Ag8.653 cells with spleen cells from a BALB/c mouse immunized with an ICAM-3/HEK transfectant.
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Research Area: Cell Biology, Immunology & Inflammation
• Note: For research use only