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Microtubule inhibitor 5

SKU: orb1688273

Description

Compound 17f is a potent small molecule microtubule inhibitor with an IC50 of 154.5 nM in NCI-H460 lung cancer cells and demonstrates high cell permeability. This agent is a valuable research tool for investigating cytoskeleton dynamics, cell division, and mechanisms of cytotoxicity in both in vitro and in vivo cancer models.

Research Area

Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

Key Properties

CAS Number2416338-55-9
MW390.36
FormulaC22H15FN2O4
SMILESC(=C\1/C(=O)N/C(=C\C2=CC=CO2)/C(=O)N1)\C3=CC(OC4=CC=C(F)C=C4)=CC=C3
TargetMicrotubule Associated,Others

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information