mGluR5 Antibody (FITC)

SKU: orb149947

Description

Mouse monoclonal to mGluR1 (FITC). The AMPA receptor is a non-NMDA-type ionotropic transmembrane receptor for glutamate that mediates fast synaptic transmission in the CNS. AMPARs are composed of four types of subunits, designated as GluR1, GluR2, GluR3 and GluR4, which combine to form tetramers..

Research Area

Signal Transduction

Images & Validation

• Tested Applications: ICC, IF, IHC, IP, WB
• Dilution Range: WB (1:1000), IHC (1:1000), ICC/IF (1:100)
• Reactivity: Human, Mouse, Rat
• Application Notes:
  1 µg/ml was sufficient for detection of mGluR1/5 glutamate receptor in 20 µg of rat brain membrane lysate and assayed by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.

Key Properties

• Host: Mouse
• Clonality: Monoclonal
• Isotype: IgG1
• Clone No.: N75/33 (Formerly sold as S75-33)
• Immunogen: Fusion protein amino acids 824-1203 (cytoplasmic C-terminus) of rat mGluR5b
• Target: mGluR5
• Molecular Weight: 130kDa
• Purification: Protein G Purified
• Conjugation: FITC

Storage & Handling

• Storage: Conjugated antibodies should be stored according to the product label
• Buffer/Preservatives: 640.91mM DMSO, 136.36 mM Ethanolamine, 126.89 mM chlorides, 9.09mM phosphates, 9.09mM NaHCO3
• Concentration: 1 mg/ml
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

mGluR5, mGlu5, GRM5, GPRC1E, Metabotropic glutamate receptor 5, Metabotropic glutamate receptor 5 variant F, Metabotropic glutamate receptor 5 variant G, Metabotropic glutamate receptor 5 variant H, Glutamate receptor metabotropic 5, mGluR5a, mGluR5b, mGluR, Glutamate receptor metabotropic 1, mGlu1, mGluR1, GRM1, GRM 1, GRM1A, GRM1 alpha, GRM1_HUMAN, GPRC1A, Metabotropic glutamate receptor 1, mGluR1 alpha

Quick Database Links

Gene Symbol

mGluR5

UniProt

P31424

NCBI Gene ID

24418

RefSeq (Protein):NP_058708.1