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Mcl-1 inhibitor 20

SKU: orb2665436

Description

Mcl-1 inhibitor20 (compound 47) is a potent and selective small molecule antagonist of Mcl-1, binding with high affinity (Ki=24 nM) to its BH3 groove. It demonstrates favorable drug-like properties, including metabolic stability and low cardiotoxicity, supporting its use in vitro and in vivo for studying apoptosis and leukemia.

Research Area

Cell Biology, Pharmacology & Drug Discovery; Cell Biology

Images & Validation

Key Properties

MW990.62
FormulaC55H61ClFN5O7S
TargetBcl-2 Family

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information