MAP2K6 Antibody

• Catalog Number: orb1732595
• Category: Antibodies
• Description: This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis. Tissue specificity: Isoform 2 is only expressed in skeletal muscle. Isoform 1, on the other hand, is found in skeletal muscle, heart, and in lesser extent in liver or pancreas.
• Species/Host: Mouse
• Clonality: Monoclonal
• Clone Number: 8C11
• Tested applications: IP, WB
• Reactivity: Human, Rat
• Isotype: Mouse IgG1
• Immunogen: Purified recombinant human MKK6 protein fragments expressed in E.coli.
• Concentration: 1mg/ml
• Dilution range: IP: 1/20; WB: 1/500-1/1000
• Conjugation: Unconjugated
• MW: Calculated MW: 37 kDa; Observed MW: 40 kDa
• Entrez: 5608
• UniProt ID: P52564
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Buffer/Preservatives: Liquid in PBS containing 50% glycerol, 0.5% rAlbumin and 0.02% sodium azide, pH 7.3.
• Alternative names: MAP2K6; MEK6; MKK6; PRKMK6; SKK3; Dual specificity
• Note: For research use only
• Expiration Date: 12 months from date of receipt.