M40

SKU: orb1679354

Description

This small molecule is a potent, non-selective galanin receptor antagonist with Ki values of 1.82 nM (GAL1) and 5.1 nM (GAL2). It blocks galanin-mediated effects, including the attenuation of fluoxetine's antidepressant action and the inhibition of galanin-induced feeding behavior in vivo, making it a valuable tool for neuropharmacology and behavioral studies.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• Target: Neuropeptide Y Receptor
• CAS Number: 143896-17-7
• MW: 1981.33
• Formula: C₉₄H₁₄₅N₂₃O₂₄
• SMILES: C([C@@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@@H](CC1=CC=C(O)C=C1)C(N[C@H](C(N[C@H](C(NCC(=O)N2[C@H](C(=O)N3[C@H](C(=O)N4[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N)=O)C)=O)CC(C)C)=O)C)=O)CC(C)C)=O)C)=O)CCC4)CCC3)CCC2)=O)CC(C)C)=O)CC(C)C)=O)=O)=O)C)=O)CO)=O)CC(N)=O)=O)CC(C)C)=O)[C@@H](C)O)=O)NC(CN)=O)C=5C=6C(NC5)=CC=CC6

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

16133821