LRRK2 Antibody

SKU: orb150586

Description

Mouse Anti-Human LRRK2 (Dardarin) Monoclonal IgG2a

Research Area

Cell Biology

Images & Validation

• Tested Applications: ICC, IF, IHC, WB
• Dilution Range: WB (1:100)
• Reactivity: Human, Rat
• Application Notes:
  10 µg/ml was sufficient for detection of LRRK2/Dardarin in 20 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

Key Properties

• Host: Mouse
• Clonality: Monoclonal
• Isotype: IgG2a
• Clone No.: N231B/34 (Formerly sold as S231B-34)
• Immunogen: Fusion protein amino acids 841-960 of human LRRK2. 81% identical in mouse, 80% identical in rat. < 30% identity with LRRK1.
• Target: LRRK2
• Molecular Weight: 200kDa
• Purification: Protein G Purified
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: PBS pH 7.4, 50% glycerol, 0.1% sodium azide. Storage buffer changes when conjugated.
• Concentration: 1 mg/ml
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

LRRK2, Leucine-rich repeat kinase 2, Leucine-rich repeat serine/threonine-protein kinase 2, RIP7, RIPK7, PARK8, Dardarin, ROCO 2, Augmented in rheumatoid arthritis 17

Quick Database Links

Gene Symbol

LRRK2

UniProt

Q5S007

NCBI Gene ID

120892

RefSeq (Protein):NP_940980