Queen's Award Received in 2021 ISO 9001 Certified Delivered over 1,000,000 bio-reagents to life science researchers Trusted by Life Science Communities
Cart summary

You have no items in your shopping cart.

Lanraplenib

SKU: orb1218607

Description

Lanraplenib is a highly selective and orally active SYK inhibitor (IC50=9.5 nM) in development for the treatment of inflammatory diseases. Lanraplenib inhibits SYK activity in platelets via the glycoprotein VI (GPVI) receptor without prolonging bleeding time (BT) in monkeys or humans.

Images & Validation

Key Properties

CAS Number1800046-95-0
MW443.5
Purity>98% (HPLC)
FormulaC23H25N9O
SMILESC1CN(CCN1C2COC2)C3=CC=C(C=C3)NC4=NC(=CN5C4=NC=C5)C6=CN=CC(=N6)N
TargetSyk
SolubilityDMSO:41.67 mg/mL (93.96 mM; Need ultrasonic)

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

GS-9876

Similar Products

  • Lanraplenib monosuccinate [orb1709277]

    1800046-97-2

    561.59

    C27H31N9O5

    100 mg, 250 mg, 1 g
  • Lanraplenib succinate [orb1709278]

    1800047-00-0

    1241.294

    C58H68N18O14

    2 mg
  • Lanraplenib [orb1309494]

    99.42% (May vary between batches)

    1800046-95-0

    443.5

    C23H25N9O

    2 mg, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 1 mg, 1 ml x 10 mM (in DMSO)
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Protocol Information

Available Sizes

Select a size below

500 mg
200 mg
2 mg
$ 130.00
5 mg
$ 180.00
10 mg
$ 280.00
25 mg
$ 490.00
50 mg
$ 710.00
100 mg
$ 1,040.00