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Lanraplenib monosuccinate
Catalog Number: orb1709277
| Catalog Number | orb1709277 |
|---|---|
| Category | Small Molecules |
| Description | Lanraplenib monosuccinate |
| CAS Number | 1800046-97-2 |
| Purity | 98% |
| MW | 561.59 |
| SMILES | O=C(O)CCC(=O)O.N1=CC(=NC(=C1)C=2N=C(NC3=CC=C(C=C3)N4CCN(CC4)C5COC5)C6=NC=CN6C2)N |
| Formula | C27H31N9O5 |
| Biological Activity | Lanraplenib monosuccinate inhibits SYK activity in platelets via the glycoprotein VI (GPVI) receptor without prolonging bleeding time (BT) in monkeys or humans. Lanraplenib monosuccinate is a highly selective and orally active SYK inhibitor (IC50=9.5 nM) in development for the treatment of inflammatory diseases. |
| Storage | -20°C |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
