Lanraplenib succinate

SKU: orb1709278

Description

Lanraplenib succinate is a potent and selective oral SYK inhibitor (IC50=9.5 nM) that blocks platelet activation via the GPVI receptor. Notably, it does not prolong bleeding time in preclinical and clinical studies, supporting its investigation for inflammatory conditions in both cellular assays and animal models.

Research Area

Cardiovascular Research, Signal Transduction

Key Properties

• CAS Number: 1800047-00-0
• MW: 1241.294
• Formula: C₅₈H₆₈N₁₈O₁₄
• SMILES: OC(=O)CCC(O)=O.OC(=O)CCC(O)=O.OC(=O)CCC(O)=O.Nc1cncc(n1)-c1cn2ccnc2c(Nc2ccc(cc2)N2CCN(CC2)C2COC2)n1.Nc1cncc(n1)-c1cn2ccnc2c(Nc2ccc(cc2)N2CCN(CC2)C2COC2)n1
• Target: Syk

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

133082362