KRAS G12C inhibitor 61

SKU: orb2277664

Description

KRAS G12C inhibitor 61 (Example 3) demonstrates potent activity by inhibiting phospho-ERK 1/2 in MIA PaCa-2 cells, with an IC50 value of 9 nM, and is applicable in the research of pancreatic, colorectal, and lung cancers.

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Key Properties

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CAS Number	2300967-40-0
MW	590.09
Formula	C₃₁H₃₃ClFN₇O₂
SMILES	O=C1N(C=2C(C(=N1)N3C(C)CN(C(C=C)=O)C(C)C3)=CC(Cl)=C(N2)C4=C(F)C=CC=C4N)C5=C(C(C)C)N=CC=C5C
Target	ERK,Kras,Ras

Storage & Handling

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Storage	-20°C
Disclaimer	For research use only

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Gene Symbol

ERK,Kras,Ras

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