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KRAS G12C-IN-76

SKU: orb3210795

Description

KRAS G12C-IN-76 (Compound 39) is an orally active inhibitor of KRASG12C that suppresses ERK phosphorylation and exhibits anticancer activity against pancreatic cancer.

Images & Validation

Key Properties

CAS Number3023465-61-1
MW727.77
FormulaC38H33F4N7O2S
SMILESC(OC=1N=C(C2=C(N1)C(F)=C(N=C2)C=3C4=C(C=CC3)C=CC(F)=C4C#C)N5[C@@H](C)CN(C(/C(=C/C6=NC=CS6)/F)=O)CC5)[C@@]78N(C[C@H](F)C7)CCC8
TargetRas,ERK

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information