Ki-67 Antibody

• Catalog Number: orb2635990
• Category: Antibodies
• Description: Proliferation marker protein Ki-67 antigen is a nuclear, non-histone protein that is present in all stages of the cell cycle except G0. This characteristic makes Ki-67 an excellent marker for proliferating cells and is commonly used as one of the prognostic factors in cancer studies. A correlation has been demonstrated between Ki-67 index and the histo-pathological grade of neoplasms. Assessment of Ki-67 expression in renal and ureter tumors shows a correlation between tumor proliferation and disease progression, thus making it possible to differentiate high-risk patients. Ki-67 expression may also prove to be important for distinguishing between malignant and benign peripheral nerve sheath tumors. Ki-67 labeling index has been shown to be a prognostic marker in a number of neoplasms including grade II astrocytoma, oligodendroglioma, colon carcinoma, and breast carcinoma. In general, Ki-67 is a good marker of proliferating cell populations.
• Clonality: Recombinant
• Species/Host: Mouse
• Isotype: Mouse IgG2b, kappa
• Conjugation: Unconjugated
• Reactivity: Human
• Immunogen: A recombinant fragment (within amino acids 2200-2500) of human MKI67 protein was used as the immunogen for the recombinant MKI67 antibody.
• UniProt ID: P46013
• Tested applications: ELISA
• Dilution range: ELISA
• Application notes: Optimal dilution of the recombinant MKI67 antibody should be determined by the researcher.
• Antibody Type: Primary Antibody
• Clone Number: rMKI67/9616
• Formula: 1 mg/ml in 1X PBS; BSA free, sodium azide free
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

SDS-PAGE analysis of purified, BSA-free recombinant MKI67 antibody (clone rMKI67/9616) as confirmation of integrity and purity.