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KDM2A (N) Antibody, Rabbit Polyclonal
Catalog Number: orb67176
| Catalog Number | orb67176 |
|---|---|
| Category | Antibodies |
| Description | Rabbit polyclonal to KDM2A.Lysine-specific demethylase 2A (KDM2A) is a histone demethylase belonging to the JHDM1 histonedemethylase family. KDM2A specifically demethylates 'Lys-36' of histone H3, thereby playing acentral role in histone code. It preferentially demethylates dimethylated H3 'Lys-36' residue while ithas weak or no activity for mono-and tri-methylated H3 'Lys-36'. KDM2A is required to maintain theheterochromatic state. It associates with centromeres and represses transcription of small non-codingRNAs encoded by the clusters of satellite repeats at the centromere. KDM2A is required to sustaincentromeric integrity and genomic stability, particularly during mitosis. |
| Species/Host | Rabbit |
| Clonality | Polyclonal |
| Tested applications | WB |
| Reactivity | Human |
| Immunogen | N-terminal region of human KDM2A |
| Purity | Affinity purification |
| Conjugation | Unconjugated |
| MW | 133 |
| UniProt ID | Q9Y2K7 |
| Storage | -20°C |
| Buffer/Preservatives | 0.01% NaN3 |
| Alternative names | anti-KDM2A antibody Read more... |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
Western blot analysis of total cell extracts from human Hela(Lane) and human Jurkat(Lane2) using KDM2A antibody
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