KDM2A (N) Antibody, Rabbit Polyclonal

SKU: orb67175

Description

Rabbit polyclonal to KDM2A.Lysine-specific demethylase 2A (KDM2A) is a histone demethylase belonging to the JHDM1 histonedemethylase family. KDM2A specifically demethylates 'Lys-36' of histone H3, thereby playing acentral role in histone code. It preferentially demethylates dimethylated H3 'Lys-36' residue while ithas weak or no activity for mono-and tri-methylated H3 'Lys-36'. KDM2A is required to maintain theheterochromatic state. It associates with centromeres and represses transcription of small non-codingRNAs encoded by the clusters of satellite repeats at the centromere. KDM2A is required to sustaincentromeric integrity and genomic stability, particularly during mitosis.

Images & Validation

• Tested Applications: WB
• Dilution range: WB:1:500-1:1000
• Reactivity: Human

Key Properties

• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: N-terminal region of human KDM2A
• Molecular Weight: 133
• Purity: Affinity purification
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: 0.01% NaN3
• Disclaimer: For research use only

Alternative Names

anti-KDM2A antibody,anti-Lysinespecific demethylase 2A antibody,anti-CXXCtype zinc finger protein 8 antibody,anti-Fbox and leucinerich repeat protein 11 antibody,anti-Fbox protein FBL7 antibody,anti-Fbox protein Lilina antibody,anti-Fbox antibody,anti-LRRrepeat protein 11 JmjC domaincontaining histone demethylation protein 1A antibody,anti-[HistoneH3]lysine36 demethylase 1A antibody,anti- CXXC8 antibody,anti-FBL7 antibody,anti-FBXL11 antibody,anti-JHDM1A antibody,anti-KIAA1004 antibody

Western blot analysis of total cell extracts from human Hela using KDM2A antibody

Quick Database Links

UniProt

Q9Y2K7