KAISO (N) Antibody, Rabbit Polyclonal

SKU: orb66924

Description

Rabbit polyclonal to KAISO.KAISO is also known as Zinc finger and BTB domain-containing protein 33, a transcriptional regulatorwith bimodal DNA-binding specificity. KAISO binds to methylated CpG dinucleotides in theconsensus sequence 5'-CGCG-3' and also binds to the non-methylated consensus sequence 5'-CTGCNA-3'. KAISO can recruits the N-CoR repressor complex to promote histone deacetylation andthe formation of repressive chromatin structures in target gene promoters. In contrast, KAISO mayalso activate transcription of a subset of target genes by the recruient of CTNND2.

Research Area

Epigenetics, Neuroscience, Signaling Pathways, Wnt

Images & Validation

• Tested Applications: WB
• Dilution Range: WB:1:1000-1:5000
• Reactivity: Human, Mouse

Key Properties

• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: N-terminal region of mouse KAISO
• Molecular Weight: 74
• Purity: Affinity purification
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: 0.01% NaN3
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

anti-KAISO antibody,anti-ZBTB33 antibody,anti-ZNF348 antibody,anti-Zinc finger and BTB domaincontaining protein 33 antibody

Western blot of total cell extracts from human MCF7, using Ab (orb66924) at RT for 2 h.

Quick Database Links

UniProt

Q8BN78