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KAISO (vPairTM) Antibodies
Catalog Number: orb131766
| Catalog Number | orb131766 |
|---|---|
| Category | Antibodies |
| Description | Rabbit polyclonal to KAISO. KAISO antibodies represent a pair of fully characterized antibodies that recognize two different regions of a target protein. The product is developed by Biorbyt to address whether the signal observed truly represents the protein of interest, an often encountered issue in antibody pairs-based assays. The use of a pair of fully characterized vPair antibodies in the same assay can validate signal specificity since vPair antibodies recognize two independent epitopes of the same protein. Different sets of vPair antibodies are developed at Biorbyt to work with specific applications, including antibody pairs arrays, Western blot, IP-Western, ChIP, IHC, and FACS. KAISO is also known as Zinc finger and BTB domain-containing protein 33, a transcriptional regulator with bimodal DNA-binding specificity. KAISO binds to methylated CpG dinucleotides in the consensus sequence 5-CGCG-3 and also binds to the non-methylated consensus sequence 5-CTGCNA-3. KAISO can recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters. In contrast, KAISO may also activate transcription of a subset of target genes by the recruitment of CTNND2. |
| Clonality | Polyclonal |
| Species/Host | Rabbit |
| Conjugation | Unconjugated |
| Reactivity | Human, Mouse |
| Concentration | 100 μg/ml BSA |
| Buffer/Preservatives | 0.01% NaN3 |
| Purity | Affinity purification |
| Immunogen | 2 distinct N-terminal regions of mouse KAISO |
| UniProt ID | Q8BN78 |
| MW | 74 |
| Tested applications | WB |
| Dilution range | WB:1:1000-1:3000 |
| Application notes | < strong>WB: The apparent protein size on WB may be different from the calculated M.W. due to modifications. < br>< strong>Experiment Notes: Rabbit polyclonal antibodies were produced by immunizing animals with GST-fusion proteins containing 2 distinct N-terminal regions of mouse KAISO. |
| Storage | -20°C |
| Alternative names | anti ZBTB33 antibody pairs, anti ZNF348 antibody p Read more... |
| Note | For research use only |
