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K 0859

SKU: orb1221679

Description

NVP-BGG463 is a novel Type II kinase inhibitor, targeting CDK2.

Images & Validation

Key Properties

CAS Number890129-26-7
MW578.6
Purity>98% (HPLC)
FormulaC30H29F3N6O3
SMILESCC(=O)Nc1cc(ncn1)Oc2ccc3c(c2)cccc3C(=O)Nc5ccc(CN4CCN(C)CC4)c(c5)C(F)(F)F
TargetTRP/TRPV Channel
SolubilityDMSO : ≥ 125 mg/mL; 216.05 mM

Bioactivity

In Vitro
BGG463 potently inhibits T315I BCR-ABL autophosphorylation and shows good oral efficacy in mouse models of CML.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

NVP-BGG463

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K 0859 (orb1221679)

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Available Sizes

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200 mg
500 mg
2 mg
$ 130.00
5 mg
$ 190.00
10 mg
$ 290.00
25 mg
$ 500.00
50 mg
$ 710.00
100 mg
$ 1,010.00