S0859

SKU: orb1227145

Description

S0859, an N-cyanosulphonamide compound, reversibly inhibit NBC-mediated pH(i) recovery (K (i)=1.7 microM, full inhibition at approximately 30 microM).

Key Properties

• CAS Number: 1019331-10-2
• MW: 530.04
• Purity: >98% (HPLC)
• Formula: C₂₉H₂₄ClN₃O₃S
• SMILES: O=C(N(CC1=CC=C(C2=CC=CC=C2S(=O)(NC#N)=O)C=C1)CC3=CC=C(C)C=C3)C4=CC=CC=C4Cl
• Target: NBC
• Solubility: DMSO: 10 mM

Bioactivity

• In Vitro:
  Treatment with NBC inhibitor S0859 significantly increased caspase-3 activity and elevated the number of apoptotic EC. S0859 is potentially important for probing the transporter's functional role in heart and other tissues.

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

S0859 | S-0859 | S 0859.

Quick Database Links

Gene Symbol

NBC