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(+)-ITD-1

SKU: orb2802297

Description

(+)-ITD-1 is a potent and selective TGF-β2 inhibitor (IC50 = 0.46 µM) that induces TGFBR2 degradation. This small molecule is a valuable research tool for studying cardiomyocyte differentiation, mesoderm formation in mESC models, and TGF-β signaling pathways in both cellular and developmental biology contexts.

Research Area

Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number1409968-46-2
MW415.52
FormulaC27H29NO3
SMILESC(OCC)(=O)C=1[C@@H](C2=C(NC1C)CC(C)(C)CC2=O)C3=CC=C(C=C3)C4=CC=CC=C4
TargetTGF-beta/Smad

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

Protocol Information