(+)-ITD-1

SKU: orb2802297

Description

(+)-ITD-1 is a potent and selective TGF-β2 inhibitor (IC50 = 0.46 µM) that induces TGFBR2 degradation. This small molecule is a valuable research tool for studying cardiomyocyte differentiation, mesoderm formation in mESC models, and TGF-β signaling pathways in both cellular and developmental biology contexts.

Research Area

Stem Cell & Developmental Biology

Key Properties

• CAS Number: 1409968-46-2
• MW: 415.52
• Formula: C₂₇H₂₉NO₃
• SMILES: C(OCC)(=O)C=1[C@@H](C2=C(NC1C)CC(C)(C)CC2=O)C3=CC=C(C=C3)C4=CC=CC=C4
• Target: TGF-beta/Smad

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

71512661