ITD-1

SKU: orb1305833

Description

ITD-1 is a highly selective small molecule inhibitor of the TGFβ signaling pathway. It is widely used in both in vitro and in vivo research to investigate fibrotic diseases, cancer biology, and stem cell differentiation, providing a precise tool for modulating this critical pathway.

Research Area

Stem Cell & Developmental Biology

Key Properties

• CAS Number: 1099644-42-4
• MW: 415.52
• Purity: 100.00%
• Formula: C₂₇H₂₉NO₃
• SMILES: CCOC(=O)C1=C(C)NC2=C(C1c1ccc(cc1)-c1ccccc1)C(=O)CC(C)(C)C2
• Target: TGF-beta/Smad
• Solubility: DMSO:8.31 mg/mL (20 mM);Ethanol:4.16 mg/mL (10.01 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.41 mM)

Bioactivity

• Target IC50:
  TGFβ:460 nM

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

ITD 1, ITD1, ITD-1, inhibit, Inhibitor, Transforming growth factor beta receptors, TGF-β Receptor, TGF-β/Smad, TGFβ, TGF-beta, TGFbeta/Smad, TGFb, TGF-b/Smad, TGFbeta, Smad

Compound Identifiers

PubChem CID

44135961