Idoxuridine

SKU: orb3032917

Description

Idoxuridine is an anti-herpesvirus antiviral and anticancer drug. It is a nucleoside analogue, a modified form of deoxyuridine, similar enough to be incorporated into viral DNA replication, but the iodine atom added to the uracil component blocks base pairing. It is used only topically due to cardiotoxicity. It was synthesized by William Prusoff in the late 1950s. Initially developed as an anticancer drug, idoxuridine became the first antiviral agent in 1962.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 54-42-2
• MW: 354.0985
• Purity: 0.98
• Formula: C₉H₁₁IN₂O₅
• SMILES: IC1C(N([H])C(N(C=1[H])[C@@]1([H])C([H])([H])[C@@]([H])([C@@]([H])(C([H])([H])O[H])O1)O[H])=O)=O

Storage & Handling

• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only