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ICILIN

SKU: orb1307393

Description

ICILIN (AG-3-5) is a potent synthetic activator of the TRPM8 ion channel. It is widely used in research to study thermosensation, cold pain, and related pathways in both cellular assays and animal models of cold hypersensitivity.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number36945-98-9
MW311.29
Purity98.64%
FormulaC16H13N3O4
SMILESOc1ccccc1N1CC=C(NC1=O)c1cccc(c1)[N+]([O-])=O
TargetTRP/TRPV Channel
SolubilityDMSO:60 mg/mL (192.75 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.42 mM)

Storage & Handling

Storagestore under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

ion, inhibit, neuroinflammation, Inhibitor, ICILIN, autoimmune, AG-3-5, channel ,cooling, receptor, potential, super, T-cell, response, Transient receptor potential channels, transient, TRPChannel, TRP Channel, TRPVChannel, TRPM8, TRPV Channel

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Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

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Protocol Information

ICILIN (orb1307393)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

1 ml x 10 mM (in DMSO)
$ 80.00
5 mg
$ 80.00
10 mg
$ 100.00
25 mg
$ 140.00
50 mg
$ 230.00
100 mg
$ 360.00
DispatchUsually dispatched within 3-5 working days
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