HSV1 Antibody / Herpes Simplex Virus Type I

• Catalog Number: orb2636480
• Category: Antibodies
• Description: The antibody reacts with HSV type 1 specific antigen. It is suitable for detection of HSV in human cellular material obtained from superficial lesions or biopsies and for the early identification of HSV in infected tissue cultures. The herpes simplex virus (HSV) (also known as cold sore, night fever or fever blister) is a virus that causes a contagious disease. There are two main types of Herpes Simplex Virus (HSV), 1 and 2. The HSV-1 strain generally appears in the orafacial organs. HSV2 usually resides in the sacral ganglion at the base of the spine. All herpes viruses are morphologically identical: they have a large double-stranded DNA genome and the virion consists of an icosahedral nucleo-capsid, which is surrounded by a lipid bilayer envelope. ICP8, the HSV1 encoded single-strand DNA (ssDNA)-binding protein, is the major DNA binding protein of HSV1. ICP8 promotes single-stranded DNA to assemble into a homologous duplex plasmid producing a displacement loop. At higher concentrations, however, ICP8 facilitates the reverse reaction due to its helix destabilizing activity.
• Clonality: Monoclonal
• Species/Host: Mouse
• Isotype: Mouse IgG1, kappa
• Conjugation: Unconjugated
• Reactivity: Human
• Immunogen: Baculovirus-expressed HSV DNA polymerase (POL) and POL/UL42 complex was used as the immunogen for the HSV1 antibody.
• Tested applications: WB
• Dilution range: Western blot: 2-4ug/ml
• Application notes: Optimal dilution of the HSV1 antibody should be determined by the researcher.
• Antibody Type: Primary Antibody
• Clone Number: HSVI/2045
• Formula: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Hazard Information: This HSV1 antibody is available for research use only.
• Note: For research use only

SDS-PAGE analysis of purified, BSA-free HSVI antibody (clone HSVI/2045) as confirmation of integrity and purity.