HLA-ABC Antibody (MHC I)

• Catalog Number: orb749553
• Category: Antibodies
• Description: Reacts with a monomorphic determinant of human major histocompatibility (MHC) class I antigens (HLA-A, B and C). Human MHC class I antigens are expressed constitutively on all nucleated cells lymphocytes such as lymphocytes, thymocytes, granulocytes, and bone marrow cells and are absent on erythrocytes. MHC class I antigens play a role in class I MHC-associated antigen presentation, inhibition of NK cell cytotoxicity, tumor surveillance, and tissue allotransplantation.
• Species/Host: Mouse
• Clonality: Monoclonal
• Clone Number: 246-B8.E7
• Tested applications: FACS, IF, WB
• Reactivity: Human, Mouse
• Isotype: Mouse IgG2a, kappa
• Immunogen: Human peripheral blood leukocytes were used as the immunogen for the HLA-ABC antibody.
• Dilution range: Western blot: 1-2ug/ml,Flow cytometry: 1-2ug/million cells,Immunofluorescence: 1-2ug/ml
• Purity: Protein G affinity chromatography
• Conjugation: Unconjugated
• Formula: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
• Hazard Information: This HLA-ABC antibody is available for research use only.
• UniProt ID: P30443, P30499, P01889
• Storage: Store the HLA-ABC antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
• Buffer/Preservatives: 0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin (US sourced) and 0.05% sodium azide
• Note: For research use only
• Application notes: Optimal dilution of the HLA-ABC antibody should be determined by the researcher.
• Expiration Date: 12 months from date of receipt.