Harmine

SKU: orb1307663

Description

Harmine, also known as Telepathine, is a beta-carboline alkaloid extracted from Peganum harmala seeds. It serves as a research tool in neuroscience and biochemistry, frequently used in vitro to study its interactions with monoamine oxidase and serotonin receptors.

Research Area

Cell Biology, Metabolism Research, Neuroscience, Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 442-51-3
• MW: 212.25
• Purity: 98.29% (May vary between batches)
• Formula: C₁₃H₁₂N₂O
• SMILES: COc1ccc2c(c1)[nH]c1c(C)nccc21
• Target: MAO,5-HT Receptor,DYRK
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (4.71 mM);DMSO:16.9 mg/mL (79.62 mM)

Bioactivity

• Target IC50:
  5-HT2A receptor:397 nM (Ki)|MAO-A:0.048 μM(Ki)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Telepathine, Serotonin Receptor, Inhibitor, inhibit, Harmine, MAO, 5HT Receptor, 5-HT Receptor, 5-hydroxytryptamine Receptor, 5HTReceptor, Dual specificity tyrosine phosphorylation regulated kinase, Dual specificity tyrosine regulated kinase, DYRK

Compound Identifiers

PubChem CID

5280953