Harmine HCl

SKU: orb1304990

Description

Harmine hydrochloride, also known as telepathine hydrochloride, is a natural alkaloid isolated from plants of the Peganum harmala genus. This compound is widely used in biochemical research as a potent and selective inhibitor of monoamine oxidase A (MAO-A) and has been investigated in vitro and in vivo for its effects on neurobiology and cell proliferation.

Research Area

Cancer Biology, Neuroscience, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 343-27-1
• MW: 248.71
• Purity: >98%
• Formula: C₁₃H₁₂N₂O·HCl
• SMILES: Cl.COc1ccc2c(c1)[nH]c1c(C)nccc21
• Target: Monoamine oxidase
• Solubility: Soluble in Water (up to 25 mg/ml).

Bioactivity

• Target IC50:
  MNB:149 nM|DYRK1A:33 nM|DYRK2:1.9 μM|DYRK1B:166 nM|5-HT2A receptor:397 nM (Ki)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Inhibitor, GluR1, Harmine, Harmine hydrochloride, Harmine Hydrochloride, inhibit, 5-hydroxytryptamine Receptor, 5HTReceptor, 5-HT Receptor, 5HT Receptor, Dual specificity tyrosine phosphorylation regulated kinase, Dual specificity tyrosine regulated kinase, DYRK1B, DYRK, DYRK2, DYRK1A, Telepathine, telepathine hydrochloride, telepathine Hydrochloride, Serotonin Receptor

Compound Identifiers

PubChem CID

5359389