GSK3 beta Rabbit mAb [KD Validated] Antibody

SKU: orb1951989

Description

Glycogen synthase kinase-3 (GSK3) is a proline-directed serine-threonine kinase that was initially identified as a phosphorylating and inactivating glycogen synthase .GSK3B is involved in energy metabolism, neuronal cell development, and body pattern formation.In skeletal muscle, it contributes to insulin regulation of glycogen synthesis by phosphorylating and inhibiting GYS1 activity and hence glycogen synthesis.

Images & Validation

• Tested Applications: FC, ICC, IHC, WB
• Dilution range: WB 1:500~1:3000 IHC 1:50~1:200 ICC/IF 1:100~1:500 FC 1:200~1:500
• Reactivity: Human, Mouse

Key Properties

• Antibody Type: Recombinant Antibody
• Host: Rabbit
• Clonality: Monoclonal
• Isotype: Rabbit IgG
• Immunogen: A synthesized peptide derived from human GSK3 beta
• Purification: Affinity-chromatography
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Disclaimer: For research use only

Alternative Names

glycogen synthase kinase 3 beta; Glycogen synthase kinase-3 beta; GSK-3 beta; GSK3B; GSK3beta isoform;

All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.

Immunofluorescent analysis of Hela cells, using GSK3 beta Antibody.

Immunohistochemical analysis of paraffin-embedded human colon carcinome, using GSK3 beta Antibody.

Western blot analysis of GSK3 beta expression in HEK293 cell lysate.

Quick Database Links

UniProt

P49841