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GSK-3β inhibitor 14

SKU: orb1685555

Description

This compound, a 1,5-benzothiazepin-4(5H)-one derivative, acts as a weak inhibitor of GSK-3β with an IC50 exceeding 100 µM. It serves as a useful research tool for investigating GSK-3β signaling pathways in cellular models of neurological disorders and diabetes.

Research Area

Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number863004-48-2
MW283.39
Purity99.97% (May vary between batches)
FormulaC17H17NOS
SMILESC(N1C=2C(SC(C)CC1=O)=CC=CC2)C3=CC=CC=C3
TargetGSK-3
SolubilityDMSO:2.88 mg/mL (10.16 mM)

Bioactivity

Target IC50
GSK-3β:﹥ 100μM

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

1,5-Benzothiazepin-4(5H)-one, 2,3-dihydro-2-methyl-5-(phenylmethyl)-, GSK-3β inhibitor 14, GSK-3β, GSK-3beta inhibitor 14, GSK-3b inhibitor 14, GSK3

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Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

1 mg
$ 80.00
5 mg
$ 120.00
10 mg
$ 150.00
25 mg
$ 230.00
50 mg
$ 320.00
100 mg
$ 420.00
DispatchUsually dispatched within 5-10 working days
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