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GSK-3β inhibitor 14

SKU: orb1685555

Description

This compound, a 1,5-benzothiazepin-4(5H)-one derivative, acts as a weak inhibitor of GSK-3β with an IC50 exceeding 100 µM. It serves as a useful research tool for investigating GSK-3β signaling pathways in cellular models of neurological disorders and diabetes.

Research Area

Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number863004-48-2
MW283.39
Purity99.97%
FormulaC17H17NOS
SMILESC(N1C=2C(SC(C)CC1=O)=CC=CC2)C3=CC=CC=C3
TargetGSK-3
SolubilityDMSO:2.88 mg/mL (10.16 mM)

Bioactivity

Target IC50
GSK-3β:﹥ 100μM

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

1,5-Benzothiazepin-4(5H)-one, 2,3-dihydro-2-methyl-5-(phenylmethyl)-, GSK-3β inhibitor 14, GSK-3β, GSK-3beta inhibitor 14, GSK-3b inhibitor 14, GSK3

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Key Properties

No computed properties available.

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Protocol Information

GSK-3β inhibitor 14 (orb1685555)

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Available Sizes

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1 mg
$ 100.00
5 mg
$ 160.00
10 mg
$ 230.00
25 mg
$ 360.00
50 mg
$ 500.00
100 mg
$ 660.00
200 mg
$ 900.00
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