TCS 21311

• Catalog Number: orb1307693
• Category: Small Molecules
• Description: TCS 21311
• Purity: ≥98%
• MW: 526.51
• Biological Activity: TCS 21311 (NIBR3049) is an effective and highly selective inhibitor of JAK3 (IC50: 8 nM). TCS 21311 inhibits PKCα, PKCθ, and GSK3β (IC50s: 13, 68, and 3 nM, respectively). It displays > 100-fold selectivity over JAK1, JAK2, and TYK2.
• CAS Number: 1260181-14-3
• Formula: C₂₇H₂₅F₃N₄O₄
• SMILES: CC(C)(O)C(=O)N1CCN(CC1)c1ccc(c(c1)C1=C(C(=O)NC1=O)c1c[nH]c2ccccc12)C(F)(F)F
• Storage: -20°C
• Note: For research use only