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Catalog Number | orb248152 |
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Category | Antibodies |
Description | G protein receptors, also called GPRs, GPCRs, and seven-transmembrane domain receptors, are a large family of receptors with possibly over 800 members. These receptors sense stimuli outside, convey the signal across the cell membrane, and activate internal signal transduction pathways and cellular responses. GPR77 is involved in the complement system of the innate immune response and may signal through the beta-arrestin pathway, and possibly act as a decoy receptor. It is co-expressed with the C5a receptor on neutrophils and may modulate C5a1 activity. |
Species/Host | Rabbit |
Clonality | Polyclonal |
Tested applications | WB |
Reactivity | Human, Primate |
Isotype | Rabbit IgG |
Immunogen | A recombinant protein fragment from the N-terminal region of human GPR77 was used as the immunogen for this antibody. |
Dilution range | Western blot: 1-3ug/ml |
Purity | Protein A Affinity Chromatography |
Conjugation | Unconjugated |
Formula | 0.5 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide |
Hazard Information | This GPR77 antibody is available for research use only. |
Entrez | 445269 |
Storage | Aliquot the GPR77 antibody and store frozen at -20°C or colder to avoid repeated freeze-thaw cycles. |
Buffer/Preservatives | 1X PBS, pH 7.4 |
Note | For research use only |
Application notes | Provided assay concentrations are suggestions only, GPR77 antibody titration may be required for optimal results. |
Expiration Date | 12 months from date of receipt. |
Western blot analysis of human samples using GPR77 antibody (primary antibody dilution at: at 1 ug/ml)
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