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Glutamine Synthetase Antibody / GLUL

Catalog Number: orb1824335

DispatchUsually dispatched within 5-10 working days
$ 780.00
Catalog Numberorb1824335
CategoryAntibodies
DescriptionGlutamine synthetase (Gl Syn) forms a homo-octamer that serves as a catalyst for the amination of glutamic acid to form glutamine. This enzyme is a marker for astrocytes, which serve as the primary site of conversion of glutamic acid to glutamine in the brain. Induction of glutamine synthetase is seen upon astrocyte cell contact with neurons. Elevated expression of glutamine synthetase in glial cells has been shown to protect neurons from degeneration due to excess glutamate. Glutamine synthetase is also present in the liver and is involved in nitrogen homeostasis. Overexpression of glutamine synthetase has been shown in primary liver cancers, indicating a potential role for glutamine synthetase in hepatocyte transformation.
Species/HostMouse
ClonalityMonoclonal
Clone NumberGLUL/6601
Tested applicationsIHC-P, WB
ReactivityCanine, Human
IsotypeMouse IgG2b, kappa
ImmunogenA recombinant partial protein sequence (within amino acids 50-250) from the human protein was used as the immunogen for the Glutamine Synthetase antibody.
Antibody TypePrimary Antibody
Dilution rangeWestern blot: 1-2ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT
ConjugationUnconjugated
Formula1 mg/ml in 1X PBS; BSA free, sodium azide free
Hazard InformationThis Glutamine Synthetase antibody is available for research use only.
UniProt IDP15104
StorageAliquot the Glutamine Synthetase antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
NoteFor research use only
Expiration Date12 months from date of receipt.
Glutamine Synthetase Antibody / GLUL

Western blot testing of human liver tissue lysate with Glutamine Synthetase antibody (clone GLUL/6601). Predicted molecular weight ~42 kDa.

Glutamine Synthetase Antibody / GLUL

Western blot testing of human Y79 cell lysate with Glutamine Synthetase antibody (clone GLUL/6601). Predicted molecular weight ~42 kDa.

Glutamine Synthetase Antibody / GLUL

IHC staining of FFPE human stomach tissue with Glutamine Synthetase antibody (clone GLUL/6601) at 2 ug/ml. Inset: PBS used in place of primary Ab (secondary Ab negative control). HIER: boil tissue sections in pH9 10 mM Tris with 1 mM EDTA for 20 min and allow to cool before testing.

Glutamine Synthetase Antibody / GLUL

IHC staining of FFPE dog liver with Glutamine Synthetase antibody (clone GLUL/6601). HIER: boil tissue sections in pH9 10 mM Tris with 1 mM EDTA for 20 min and allow to cool before testing.

  • Glutamine Synthetase Antibody / GLUL [orb1824336]

    IHC-P,  WB

    Canine, Human

    Mouse

    Monoclonal

    Unconjugated

    20 μg
  • Glutamine Synthetase Antibody / GLUL [orb1824337]

    IHC-P,  WB

    Canine, Human

    Mouse

    Monoclonal

    Unconjugated

    100 μg
  • Glutamine Synthetase Antibody / GLUL [orb1151752]

    IHC-P,  WB

    Human

    Mouse

    Monoclonal

    Unconjugated

    100 μg
  • Glutamine Synthetase Antibody / GLUL [orb2637135]

    IHC-P,  WB

    Human

    Mouse

    Monoclonal

    Unconjugated

    20 μg
  • Glutamine Synthetase Antibody / GLUL [orb1151787]

    IHC-P,  WB

    Human

    Mouse

    Monoclonal

    Unconjugated

    100 μg