Ginkgolide A

SKU: orb1305075

Description

Ginkgolide A (BN-52020) is a potent platelet-activating factor (PAF) receptor antagonist isolated from Ginkgo biloba. It is widely used in research on inflammatory and allergic diseases, with demonstrated activity in both in vitro binding assays and in vivo models of asthma, shock, and ischemia-reperfusion injury.

Research Area

Metabolism Research, Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 15291-75-5
• MW: 408.40
• Purity: 99.81% (May vary between batches)
• Formula: C₂₀H₂₄O₉
• SMILES: [H][C@]12C[C@@]34[C@H]5C[C@@H](C(C)(C)C)[C@@]33[C@@H](O)C(=O)O[C@@]3([H])O[C@@]4(C(=O)O5)[C@@]1(O)[C@H](C)C(=O)O2
• Target: Endogenous Metabolite,GABA Receptor
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2.00 mg/mL (4.90 mM);DMSO:75.00 mg/mL (183.64 mM);Ethanol:2.00 mg/mL (4.90 mM);H2O:< 1 mg/mL (insoluble or slightly soluble)

Bioactivity

• Target IC50:
  GABA receptor:14.5 μM(Ki)

Storage & Handling

• Storage: store under nitrogen,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

inhibit, Inhibitor, EndogenousMetabolite, Ginkgolide A, GABA Receptor, GABAReceptor, GABAR, Gamma-aminobutyric acid Receptor, Endogenous Metabolite, BN 52020, BN52020, BN-52020, γ-Aminobutyric acid Receptor

Compound Identifiers

PubChem CID

9909368