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Flavokawain B

SKU: orb1225916

Description

Flavokawain B is a natural chalcone that can induce apoptosis in androgen receptor-negative, hormone-refractory prostate cancer cell lines (IC50=3-50 uM), via up-regulation of death-receptor 5 and Bim expression; induces apoptosis in human myeloid leukemic cells by modifying NF-κB, possesses potential anti-inflammation and anti-cancer activities; also exhibits significant inhibition of the neurogenic nociceptive induced by intraplantar injections of glutamate and capsaicin in mice.

Images & Validation

Key Properties

CAS Number1775-97-9
MW284.311
Purity>98% (HPLC)
FormulaC17H16O4
SMILESO=C(C1=C(OC)C=C(OC)C=C1O)/C=C/C2=CC=CC=C2
TargetApoptosis
SolubilityChloroform: Soluble Dichloromethane: SolubleEthyl Acetate: SolubleAcetone: SolubleDMSO: 38 mg/mL (133.7 mM) ( < 1 mg/ml refers to the product slightly soluble or insoluble )

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Flavokawain B | Flavokawain-B | FlavokawainB

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Flavokawain B (orb1225916)

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% DMSO +
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% Tween 80 +
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Available Sizes

Select a size below

5 mg
$ 240.00
10 mg
$ 370.00
25 mg
$ 600.00
50 mg
$ 860.00
100 mg
$ 1,160.00
500 mg
$ 2,310.00