Queen's Award Received in 2021 ISO 9001 Certified Delivered over 1,000,000 bio-reagents to life science researchers Trusted by Life Science Communities
Cart summary

You have no items in your shopping cart.

Flavokawain A

SKU: orb1222348

Description

Flavokawain A has anti-tumor activity, such as inhibits growth of bladder tumor cells in a nude mice model , prevents the recurrence and progression of non-muscle-invasive urothelial cell carcinoma. Flavokawain A can significantly reduce the expression of CDK1-inhibitory kinases, Myt1 and Wee1, and cause cyclin B1 protein accumulation leading to CDK1 activation in T24 cells. Flavokawain A may exert anti-inflammatory responses by suppressing LPS-induced expression of pro-inflammatory mediators via blockage of NF-κB-AP-1-JNK/p38 MAPK signaling pathways in the murine macrophages.

Images & Validation

Key Properties

CAS Number3420-72-2
MW314.33
Purity>98% (HPLC)
FormulaC18H18O5
SMILESCOC1=CC=C(C=C1)C=CC(=O)C2=C(C=C(C=C2OC)OC)O
TargetAromatase
SolubilityIn Vitro: DMSO : 100 mg/mL (318.14 mM)

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Similar Products

  • Flavokawain A [orb609322]

    ≥98%

    64680-84-8

    314.33

    C18H18O5

    10 mg, 5 mg
  • Flavokawain B [orb1300239]

    >99.99% (May vary between batches)

    1775-97-9

    284.31

    C17H16O4

    5 mg, 10 mg, 1 mg, 25 mg, 50 mg, 100 mg
  • (Iso)-Flavokawain A [orb1303413]

    99.72% (May vary between batches)

    3420-72-2

    314.332

    C18H18O5

    100 mg, 50 mg, 1 ml x 10 mM (in DMSO)
  • 4′,6′-Dimethoxy-2′,4-dihydroxychalcone [orb1684603]

    56798-34-6

    300.31

    C17H16O5

    10 mg
  • Flavokawain C [orb1301523]

    99.94% (May vary between batches)

    37308-75-1

    300.31

    C17H16O5

    1 mg, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 1 ml x 10 mM (in DMSO)
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Protocol Information

Available Sizes

Select a size below

200 mg
500 mg
50 mg
$ 90.00
100 mg
$ 120.00