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Catalog Number | orb1303413 |
---|---|
Category | Small Molecules |
Description | Flavokawain A |
Purity | 99.72% |
MW | 314.33 |
Biological Activity | NSC-37445 has anti-tumor activity, such as inhibits growth of bladder tumor cells in a nude mice model , prevents the recurrence and progression of non-muscle-invasive urothelial cell carcinoma. NSC-37445 can significantly reduce the expression of CDK1-inhibitory kinases, Myt1 and Wee1, and cause cyclin B1 protein accumulation leading to CDK1 activation in T24 cells. 3. Flavokawain A (Flavokavain A) may exert anti-inflammatory responses by suppressing LPS-induced expression of pro-inflammatory mediators via blockage of NF-κB-AP-1-JNK/p38 MAPK signaling pathways in the murine macrophages. |
CAS Number | [3420-72-2] |
Formula | C18H18O5 |
SMILES | COc1ccc(\C=C\C(=O)c2c(O)cc(OC)cc2OC)cc1 |
Storage | -20°C |
Note | For research use only |
99.70% | |
[37951-13-6] | |
314.33 | |
C18H18O5 |
> 98% (HPLC) | |
37308-75-1 | |
300.3 | |
C17H16O5 |